Pfizer Scheme to Churn Out ‘Variant-Specific’ Vaccines Will Lead to More Variants, Experts Warn
Pfizer CEO Albert Bourla told Fox News the company has a system in place to turn around a variant-specific jab within 95 days in the likelihood a vaccine-resistant COVID strain emerges, but experts warn that strategy will backfire.
Pfizer CEO Albert Bourla on Tuesday told Fox News the company believes a COVID vaccine-resistant variant will likely one day emerge, but the company has a system in place to turn around a variant-specific jab within 95 days if it does.
“Every time a variant appears in the world, our scientists are getting their hands around it,” Bourla said. “And they are researching to see if this variant can escape the protection of our vaccine.”
Bourla said Pfizer hasn’t identified any variants that could escape the vaccine yet. However, that statement contradicts the findings of numerous studies by the Centres for Disease Control and Prevention (CDC) which show waning immunity against the Delta variant.
Bourla said Pfizer could produce new versions of its vaccine to combat a variant within three months of its discovery.
“We have built a process that within 95 days from the day we identify a variant as a variant of concern, we will be able to have a vaccine tailor-made against this variant,” Bourla said.
Public health officials have said for months universal vaccination across the U.S. and population abroad would reduce the opportunity for the virus to further mutate and evade vaccines.
The UK government’s advisory panel, the Scientific Advisory Group for Emergencies, said higher rates of virus circulation and transmission were creating “more opportunities for new variants to emerge.”
Dr Peter McCullough, board certified in internal medicine, cardiovascular diseases and clinical lipidology, said in a recent podcast: “There are clearly sources of information to suggest that once we start vaccination and we get more than 25% of the population vaccinated, we will allow one of the variants that’s in the background to emerge because it’s resistant to the vaccine.”
“That [theory] makes sense,” McCullough said. “Just like an antibiotic, once we get to a certain percentage of coverage with an antibiotic, we’ll allow a resistant bacteria to move forward.”
“If we were to go back in time six months ago, we had about 14 strains or more in the United States — all relatively small proportions. We had UK, Brazilian and there was always some Delta, by the way — it was always in the background. And there was a paper by Niessen and colleagues from Boston and Rochester Minnesota, a great paper — over a million sequenced samples. They looked at vaccination rates all over, and the variant proportions, and they concluded that with more than 25% of the population vaccinated, you’ll encourage a dominant strain to move forward.
“We’ve in a sense created now a super-dominant strain, we’ve encouraged a super-dominant strain,” though McCullough noted science showed the Delta variant is milder.
In an interview on “RFK, Jr. The Defender Podcast,” McCullough cited an Aug. 10 study in The Lancet that showed people who are vaccinated against COVID are more susceptible to the Delta variant.
According to McCullough, the paper’s authors demonstrated widespread vaccine failure and transmission under tightly controlled circumstances in a hospital lockdown in Ho Chi Minh City, Viet Nam.
Geert Vanden Bossche is a virologist and vaccinologist who worked with GSK Biologicals, Novartis Vaccines, Solvay Biologicals, Bill & Melinda Gates Foundation’s Global Health Discovery team in Seattle and GAVI, The Global Alliance for Vaccines and Immunization in Geneva.
In an Aug. 12 article, Vanden Bossche said universal mass vaccination will prompt dominant propagation of highly infectious, neutralization escape mutants, and naturally acquired — or vaccinal neutralizing antibodies — will no longer offer any protection to immunized individuals, whereas high infectious pressure will continue to suppress the innate immune defence system of the unvaccinated.
“This is to say that every further increase in vaccine coverage rates will further contribute to forcing the virus into resistance to neutralising, S-specific Abs [antibodies]. Increased viral infectivity, combined with evasion from antiviral immunity, will inevitably result in an additional toll taken on human health and human lives,” Vanden Bossche said.
As far back as March, Vanden Bossche said:
“There can be no doubt that continued mass vaccination campaigns will enable new, more infectious viral variants to become increasingly dominant and ultimately result in a dramatic incline in new cases despite enhanced vaccine coverage rates. There can be no doubt either that this situation will soon lead to complete resistance of circulating variants to the current vaccines.”
Vanden Bossche said a combination of lockdowns and extreme selection pressure on the virus and global mass vaccination might diminish the number of cases, hospitalisations and deaths in the short-term, but ultimately, would induce the creation of more escape mutants.
This will trigger vaccine companies to further refine vaccines that will add to the selection pressure, producing ever more transmissible and potentially deadly variants, he added.
According to Dr Robert Malone, inventor of mRNA and DNA vaccines, worldwide expert in RNA technologies and Harvard-trained physician, even if we had complete uptake in vaccines and complete masking, CDC data makes it clear that at best we can slow the spread of Delta but we can’t stop it.
Malone, who believes death and disability still warrant vaccination in high-risk populations, subscribes to Vanden Bossche’s theory that continued mass vaccination campaigns will enable new, more infectious viral variants.
“Geert Vanden Bossche — I am on board with that now,” Malone said, “that we really shouldn’t be doing universal vaccination because we’re just going to be generating escape mutants.”
Five CDC studies show waning vaccine immunity to Delta variant
One study found vaccine effectiveness among frontline healthcare workers declined by nearly 30 percentage points since the Delta variant became the dominant strain in the U.S. The analysis also concluded COVID vaccines were only 80% effective in preventing infection among the frontline healthcare workers.
The second study examined 43,000 Los Angeles residents 16 and older. Between May 1 and July 25, 25.3% of COVID infections occurred in fully vaccinated persons and 3.3% were in partially vaccinated persons.
The CDC cautioned in its report that vaccine effectiveness “might also be declining as time since vaccination increases and because of poor precision in estimates due to limited number of weeks of observation.”
The publication of the new studies comes a week after the CDC released its first three reports on vaccine efficacy — which also showed waning vaccine protection against the Delta variant.
The CDC’s Walensky said during an Aug. 18 press briefing the data demonstrates vaccine effectiveness against SARS-CoV-2 infection is waning over time against the Delta variant.
One study assessed Pfizer and Moderna’s effectiveness against infections among nursing home residents, and found it dropped from 75% pre-Delta to 53% when Delta became dominant. The study didn’t differentiate between asymptomatic, symptomatic and severe infections.
Another study used data from 21 hospitals to estimate the effectiveness of Pfizer and Moderna mRNA vaccines against hospitalisation over time. Among 1,129 patients who received two doses of a mRNA vaccine, vaccine effectiveness was 86% 2 to12 weeks after vaccination and 84% at 13 to 24 weeks.
The third study, using New York state data, found all three vaccines’ effectiveness against infection dropped from 92% in early May to 80% at the end of July, but the effectiveness against hospitalisation remained relatively stable.
As The Defender reported Aug. 23, the U.S. Food and Drug Administration (FDA) granted full approval to Pfizer’s COVID vaccine for people 16 years and older — without allowing public discussion or holding a formal advisory committee meeting to discuss data.